SGK1

Across TCGA patient cohorts, SGK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,449 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SGK1-associated proteins across cancer lineages are PPP1R18_S224, LMNA_S423, and MPLKIP_S133. Each is linked with SGK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SGK1-to-partner and partner-to-SGK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGK1 versus PPP1R18_S224 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGK1→partner) and Y-score (partner→SGK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP1R18_S224 →	+0.544	+0.542	<.001	.008	3	5
BRCA	LMNA_S423 →	+1.577	+1.042	<.001	<.001	3	5
OV	MPLKIP_S133 →	+0.611	+0.927	.003	.002	3	5
OV	NELFA →	-0.231	-0.649	.006	.005	3	5
LSCC	MAVS_S222 →	+0.767	+0.710	.002	.002	3	5
GBM	WAS →	+0.604	+0.811	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,449 associations by consensus.

SGK1 vs PPP1R18_S224 — BRCA

Explore this scatter interactively →