SGK1

Across TCGA patient cohorts, SGK1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,978 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SGK1-associated genes across cancer lineages are CSF2RB, CD40, and MEFV. Each is linked with SGK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SGK1-to-partner and partner-to-SGK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGK1 versus CSF2RB in UCEC, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGK1→partner) and Y-score (partner→SGK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CSF2RB →	+1.929	+1.946	.001	.001	3	1
UCEC	CD40 →	+2.019	+1.908	.002	.003	3	1
UCEC	MEFV →	+0.993	+1.889	.007	<.001	3	1
UCEC	AQP9 →	+1.244	+1.667	.001	.001	3	1
UCEC	SHD →	+0.330	+1.454	.002	.004	3	1
UCEC	ICAM2 →	+0.964	+2.067	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,978 associations by consensus.

SGK1 vs CSF2RB — UCEC

Explore this scatter interactively →