SGK1

Across TCGA cell cohorts, SGK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,681 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SGK1-associated GO terms across cancer lineages are Renal sodium ion transport, Renal sodium ion absorption, and Postsynapse to nucleus signaling pathway. Each is linked with SGK1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SGK1-to-partner and partner-to-SGK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal sodium ion transport grouped by SGK1-low versus SGK1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGK1→partner) and Y-score (partner→SGK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Renal sodium ion transport →	+0.326	+2.769	<.001	.003	3	12
LIVER	Renal sodium ion absorption →	+0.326	+2.769	<.001	.003	3	12
BLOOD_Lymphoma	Postsynapse to nucleus signaling pathway →	+0.143	+2.196	<.001	<.001	3	11
STOMACH	Regulation of focal adhesion assembly →	+0.135	+2.644	<.001	<.001	3	10
STOMACH	Regulation of cell-substrate junction assembly →	+0.135	+2.644	<.001	<.001	3	10
BREAST	Cellular response to starvation →	+0.045	+2.827	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,681 associations by consensus.

Renal sodium ion transport by SGK1 expression — LIVER

Explore this box plot interactively →