SGIP1

Across TCGA cell cohorts, SGIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,392 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SGIP1-associated GO terms across cancer lineages are Electron transport chain, Purine ribonucleoside triphosphate metabolic process, and Aerobic electron transport chain. Each is linked with SGIP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SGIP1-to-partner and partner-to-SGIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Electron transport chain grouped by SGIP1-low versus SGIP1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGIP1→partner) and Y-score (partner→SGIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Electron transport chain →	+0.068	+1.613	.009	.003	3	7
BLOOD_Leukemia	Purine ribonucleoside triphosphate metabolic process →	+0.043	+0.364	.003	.001	3	7
BLOOD_Leukemia	Aerobic electron transport chain →	+0.048	+0.240	.003	.008	3	6
BLOOD_Leukemia	ATP synthesis coupled electron transport →	+0.050	+0.267	.002	.004	3	6
BLOOD_Leukemia	Mitochondrial ATP synthesis coupled electron transport →	+0.050	+0.267	.002	.004	3	6
SOFT_TISSUE	Aerobic respiration →	+0.048	+0.974	.002	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,392 associations by consensus.

Electron transport chain by SGIP1 expression — OVARY

Explore this box plot interactively →