SGF29

Across TCGA patient cohorts, SGF29 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SGF29-associated genes across cancer lineages are eEF2, ERK2, and GAPDH. Each is linked with SGF29 in more than 1 cancer types. Because this analysis shows association rather than direction, both SGF29-to-partner and partner-to-SGF29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by SGF29-low versus SGF29-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGF29→partner) and Y-score (partner→SGF29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.485	+3.321	.001	.010	3	1
UCEC	ERK2 →	+0.281	+2.115	<.001	.017	3	1
UCEC	GAPDH →	+0.528	+2.321	.024	.034	3	1
UCEC	JNK2 →	+0.346	+3.331	<.001	.005	3	1
UCEC	MSH6 →	-0.552	-2.321	<.001	.033	3	1
UCEC	p21 →	+0.182	+2.321	.030	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

eEF2 by SGF29 expression — UCEC

Explore this box plot interactively →