SGF29

Across TCGA pan-cancer cohorts, SGF29 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of SGF29’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SGF29 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SGF29 is over-expressed in tumor, although a few such as LUAD and BLCA show the opposite, repressed pattern.

KIRC, LUAD, and KIRP are the cancer types where SGF29 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SGF29 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+0.754	<.001	12	view →
LUAD	Male	II,III,IV	−0.799	<.001	9	view →
KIRP	Male	II,III,IV	+0.671	<.001	9	view →
LIHC	All	II,III,IV	+0.852	<.001	8	view →
BLCA	Male	IV	−0.769	.002	7	view →
UCEC	All	II,III,IV	−1.051	<.001	6	view →
LUSC	All	All	−0.308	<.001	6	view →
THCA	All	All	−0.222	.004	5	view →
CHOL	All	All	+0.642	.007	2	view →
COAD	Female	All	+0.390	.021	2	view →
HNSC	Male	III,IV	+0.363	.033	2	view →
PRAD	All	All	−0.199	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

SGF29–KIRC

Open the KIRC breakdown →