SGCE

Across TCGA cell cohorts, SGCE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,123 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SGCE-associated GO terms across cancer lineages are Vesicle-mediated intercellular transport, Positive regulation of cytoskeleton organization, and Negative regulation of endothelial cell proliferation. Each is linked with SGCE in more than 12 cancer types. Because this analysis shows association rather than direction, both SGCE-to-partner and partner-to-SGCE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated intercellular transport grouped by SGCE-low versus SGCE-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGCE→partner) and Y-score (partner→SGCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Vesicle-mediated intercellular transport →	+1.304	+2.071	<.001	<.001	3	13
BONE	Positive regulation of cytoskeleton organization →	+0.092	+2.221	<.001	<.001	3	10
BLOOD_Myeloma	Negative regulation of endothelial cell proliferation →	+0.133	+3.174	.003	.002	3	9
BONE	Maintenance of location in cell →	+0.074	+1.538	.002	.002	3	9
BONE	Positive regulation of supramolecular fiber organization →	+0.106	+2.136	<.001	<.001	3	9
BONE	Positive regulation of stress fiber assembly →	+0.140	+1.627	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,123 associations by consensus.

Vesicle-mediated intercellular transport by SGCE expression — BLOOD_Lymphoma

Explore this box plot interactively →