SGCD

Across TCGA patient cohorts, SGCD protein abundance is significantly associated with the RNA expression of many other genes, with 14,393 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SGCD-associated genes across cancer lineages are FGF7, RBMS3, and LMOD1. Each is linked with SGCD in more than 9 cancer types. Because this analysis shows association rather than direction, both SGCD-to-partner and partner-to-SGCD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGCD versus FGF7 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGCD→partner) and Y-score (partner→SGCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FGF7 →	+1.769	+0.773	<.001	<.001	3	10
BRCA	RBMS3 →	+0.887	+0.709	<.001	<.001	3	10
UCEC	LMOD1 →	+1.608	+0.802	<.001	<.001	3	10
HNSC	SYNPO2 →	+1.426	+0.829	<.001	<.001	3	10
BRCA	MSRB3 →	+1.540	+0.836	<.001	<.001	3	10
GBM	PABPC5 →	+0.980	+0.698	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,393 associations by consensus.

SGCD vs FGF7 — OV

Explore this scatter interactively →