SGCB

Across TCGA cell cohorts, SGCB RNA expression is significantly associated with the go_rna of many other GO terms, with 6,287 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SGCB-associated GO terms across cancer lineages are Regulation of cilium assembly, Cell division, and Regulation of transforming growth factor beta receptor signaling pathway. Each is linked with SGCB in more than 12 cancer types. Because this analysis shows association rather than direction, both SGCB-to-partner and partner-to-SGCB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cilium assembly grouped by SGCB-low versus SGCB-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGCB→partner) and Y-score (partner→SGCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of cilium assembly →	+0.069	+1.704	<.001	<.001	3	13
BREAST	Cell division →	+0.080	+1.900	<.001	<.001	3	13
BONE	Regulation of transforming growth factor beta receptor signaling pathway →	+0.060	+1.460	.002	<.001	3	12
BONE	Regulation of focal adhesion assembly →	+0.144	+1.393	<.001	<.001	3	12
SKIN	Golgi vesicle transport →	+0.058	+1.243	<.001	<.001	3	12
OESOPHAGUS	Regulation of metaphase/anaphase transition of cell cycle →	+0.153	+1.588	<.001	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,287 associations by consensus.

Regulation of cilium assembly by SGCB expression — LUNG_NSCLC_LUSC

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