Across TCGA patient cohorts, SFXN4 mutation is significantly associated with the RNA expression of many other genes, with 727 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SFXN4-associated genes across cancer lineages are MIR8076, HPRT1P3, and RNA5SP422. Each is linked with SFXN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFXN4-to-partner and partner-to-SFXN4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFXN4→partner) and Y-score (partner→SFXN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR8076 →	+0.221	+3.436	<.001	.005	3	2
SKCM	HPRT1P3 →	+0.041	+4.411	<.001	.005	3	2
UCEC	RNA5SP422 →	+0.644	+2.086	.003	.009	3	2
UCEC	RNA5SP416 →	+0.548	+2.224	<.001	.009	3	2
UCEC	FKBP14 →	+0.663	+3.329	.001	.005	3	2
UCEC	COX15 →	+0.446	+3.329	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 727 associations by consensus.

Exploration

SFXN4 survival (RNA) · tumor vs normal (RNA) · all SFXN4 data types