SFTPA1

Across TCGA patient cohorts, SFTPA1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,884 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SFTPA1-associated genes across cancer lineages are URGCP, ABCC5, and HTRA2. Each is linked with SFTPA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFTPA1-to-partner and partner-to-SFTPA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFTPA1 versus URGCP in LSCC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPA1→partner) and Y-score (partner→SFTPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	URGCP →	-0.363	-0.592	<.001	<.001	3	2
LSCC	ABCC5 →	-1.253	-0.615	<.001	.001	3	2
LSCC	HTRA2 →	-0.370	-0.556	<.001	.001	3	2
LSCC	ACADL →	+0.625	+0.500	<.001	<.001	3	2
LSCC	EFEMP1 →	+1.034	+0.769	<.001	<.001	3	2
LUAD	SLC46A2 →	+1.101	+0.697	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,884 associations by consensus.

SFTPA1 vs URGCP — LSCC

Explore this scatter interactively →