SFTPA1

Across TCGA cell cohorts, SFTPA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 624 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SFTPA1-associated GO terms across cancer lineages are Glycerolipid biosynthetic process, Purine ribonucleoside triphosphate metabolic process, and Regulation of lipophagy. Each is linked with SFTPA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SFTPA1-to-partner and partner-to-SFTPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerolipid biosynthetic process grouped by SFTPA1-low versus SFTPA1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTPA1→partner) and Y-score (partner→SFTPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Glycerolipid biosynthetic process →	+0.038	+0.102	.004	.008	3	6
BONE	Purine ribonucleoside triphosphate metabolic process →	+0.074	+0.064	.002	.009	3	5
BLOOD_Leukemia	Regulation of lipophagy →	+0.078	+0.071	.003	.005	3	5
BLOOD_Leukemia	Positive regulation of lipophagy →	+0.078	+0.071	.003	.005	3	5
LUNG_NSCLC_LUAD	Globus pallidus development →	+1.268	+2.226	<.001	.003	3	4
LUNG_NSCLC_LUAD	Positive thymic T cell selection →	-0.827	-1.128	<.001	.006	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 624 associations by consensus.

Glycerolipid biosynthetic process by SFTPA1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →