Across TCGA patient cohorts, SFTA2 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SFTA2-associated genes across cancer lineages are MTND1P26, MTCO1P46, and RPS15AP25. Each is linked with SFTA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFTA2-to-partner and partner-to-SFTA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFTA2→partner) and Y-score (partner→SFTA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MTND1P26 →	+0.081	+4.282	<.001	.009	3	1
SKCM	MTCO1P46 →	+0.046	+3.819	<.001	.009	3	1
SKCM	RPS15AP25 →	+0.175	+4.310	<.001	.003	3	1
SKCM	RNU7-194P →	+0.581	+5.665	<.001	<.001	3	1
SKCM	RN7SL310P →	+0.086	+4.495	<.001	.007	3	1
UCEC	RNU105C →	+0.232	+4.484	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

SFTA2 survival (RNA) · tumor vs normal (RNA) · all SFTA2 data types