SFT2D3

Across TCGA patient cohorts, SFT2D3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,579 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SFT2D3-associated genes across cancer lineages are PAPLN, MFSD9, and CHST4. Each is linked with SFT2D3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SFT2D3-to-partner and partner-to-SFT2D3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFT2D3 versus PAPLN in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFT2D3→partner) and Y-score (partner→SFT2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PAPLN →	-0.889	-0.535	<.001	<.001	3	3
HNSC	MFSD9 →	+0.525	+0.438	.003	.004	3	3
OV	CHST4 →	+0.947	+0.394	.006	.002	3	3
OV	TMEM208 →	+0.546	+0.383	.003	.001	3	3
LSCC	SLCO2B1 →	-0.666	-0.267	<.001	.003	3	3
HNSC	FRAS1 →	+0.873	+0.408	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,579 associations by consensus.

SFT2D3 vs PAPLN — UCEC

Explore this scatter interactively →