SFRP2

Across TCGA patient cohorts, SFRP2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,777 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SFRP2-associated genes across cancer lineages are COL10A1, COL6A3, and MSRB3. Each is linked with SFRP2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SFRP2-to-partner and partner-to-SFRP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SFRP2 versus COL10A1 in OV, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFRP2→partner) and Y-score (partner→SFRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COL10A1 →	+2.522	+1.765	<.001	<.001	3	9
GBM	COL6A3 →	+2.369	+1.464	.001	<.001	3	9
BRCA	MSRB3 →	+1.536	+1.234	<.001	<.001	3	9
BRCA	CALHM5 →	+0.951	+1.244	<.001	<.001	3	9
OV	NUAK1 →	+1.325	+1.956	<.001	<.001	3	9
BRCA	MYL9 →	+1.205	+1.118	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,777 associations by consensus.

SFRP2 vs COL10A1 — OV

Explore this scatter interactively →