SFRP2

Across TCGA cell cohorts, SFRP2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SFRP2-associated genes across cancer lineages are RBP3, OR10W1, and PFN3. Each is linked with SFRP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SFRP2-to-partner and partner-to-SFRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBP3 grouped by SFRP2-low versus SFRP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SFRP2→partner) and Y-score (partner→SFRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RBP3 →	+0.019	+3.339	<.001	.006	3	2
LARGE_INTESTINE	OR10W1 →	+0.024	+5.562	<.001	<.001	3	1
LARGE_INTESTINE	PFN3 →	+0.169	+4.467	<.001	.004	3	1
BLOOD_Leukemia	C16orf92 →	+0.136	+4.359	<.001	<.001	3	1
BLOOD_Leukemia	GSG1L2 →	+0.028	+3.969	<.001	.009	3	1
BLOOD_Leukemia	TSPAN19 →	+0.202	+3.847	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RBP3 by SFRP2 expression — BLOOD_Leukemia

Explore this box plot interactively →