SF3B5

Across TCGA patient cohorts, SF3B5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,629 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SF3B5-associated proteins across cancer lineages are VTA1, HBS1L, and TCP1. Each is linked with SF3B5 in more than 5 cancer types. Because this analysis shows association rather than direction, both SF3B5-to-partner and partner-to-SF3B5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SF3B5 versus VTA1 in OV, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3B5→partner) and Y-score (partner→SF3B5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VTA1 →	+0.501	+0.848	<.001	<.001	3	6
OV	HBS1L →	+0.580	+0.812	.002	.004	2	6
GBM	TCP1 →	+0.239	+0.507	<.001	<.001	3	5
UCEC	CCT5 →	+0.242	+1.165	<.001	<.001	3	5
BRCA	MDN1 →	+0.361	+0.478	<.001	.001	3	5
LSCC	REPS1 →	+0.227	+0.296	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,629 associations by consensus.

SF3B5 vs VTA1 — OV

Explore this scatter interactively →