SF3B4

Across TCGA patient cohorts, SF3B4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,678 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SF3B4-associated proteins across cancer lineages are C1orf35, DHX9, and GATAD2B. Each is linked with SF3B4 in more than 7 cancer types. Because this analysis shows association rather than direction, both SF3B4-to-partner and partner-to-SF3B4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SF3B4 versus C1orf35 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3B4→partner) and Y-score (partner→SF3B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	C1orf35 →	+0.531	+1.117	<.001	<.001	3	8
LSCC	DHX9 →	+0.272	+0.713	<.001	<.001	3	8
GBM	GATAD2B →	+0.321	+0.312	<.001	<.001	3	8
LSCC	SF3B3 →	+0.210	+0.670	<.001	<.001	3	7
LSCC	ZNF687 →	+0.382	+0.763	<.001	<.001	3	7
LSCC	TMPO →	+0.360	+0.574	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,678 associations by consensus.

SF3B4 vs C1orf35 — HNSC

Explore this scatter interactively →