Across TCGA cell cohorts, SF3B3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,539 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SF3B3-associated GO terms across cancer lineages are Positive regulation of nuclear cell cycle DNA replication, mRNA alternative polyadenylation, and Mitotic DNA replication. Each is linked with SF3B3 in more than 16 cancer types. Because this analysis shows association rather than direction, both SF3B3-to-partner and partner-to-SF3B3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3B3→partner) and Y-score (partner→SF3B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of nuclear cell cycle DNA replication →	+0.135	+0.620	.008	.006	3	17
BREAST	mRNA alternative polyadenylation →	+0.096	+1.032	<.001	<.001	3	17
BONE	Mitotic DNA replication →	+0.201	+0.941	<.001	<.001	3	17
BONE	Regulation of DNA-templated DNA replication →	+0.129	+0.922	<.001	<.001	3	17
LIVER	snRNA processing →	+0.088	+0.560	.001	.007	3	16
SOFT_TISSUE	DNA integrity checkpoint signaling →	+0.089	+0.720	<.001	.004	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,539 associations by consensus.

Exploration

SF3B3 survival (RNA) · tumor vs normal (RNA) · all SF3B3 data types