Across TCGA patient cohorts, SF3A3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,483 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SF3A3-associated proteins across cancer lineages are MCM3, NASP, and MCM2. Each is linked with SF3A3 in more than 8 cancer types. Because this analysis shows association rather than direction, both SF3A3-to-partner and partner-to-SF3A3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3A3→partner) and Y-score (partner→SF3A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCM3 →	+0.807	+0.348	<.001	<.001	3	9
GBM	NASP →	+0.655	+0.364	<.001	<.001	3	8
GBM	MCM2 →	+0.791	+0.363	<.001	<.001	3	8
GBM	MCM7 →	+0.775	+0.374	<.001	<.001	3	8
PDAC	TTC4 →	+0.341	+0.389	<.001	<.001	3	7
GBM	YTHDF2 →	+0.483	+0.477	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,483 associations by consensus.

Exploration

SF3A3 survival (RNA) · tumor vs normal (RNA) · all SF3A3 data types