Across TCGA patient cohorts, SF3A3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,512 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SF3A3-associated genes across cancer lineages are NOP56, WDR74, and ILF2. Each is linked with SF3A3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SF3A3-to-partner and partner-to-SF3A3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SF3A3→partner) and Y-score (partner→SF3A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NOP56 →	+0.792	+0.150	<.001	<.001	3	7
BRCA	WDR74 →	+0.652	+0.220	<.001	<.001	3	7
HNSC	ILF2 →	+1.005	+0.173	.001	<.001	3	7
GBM	LIN9 →	+0.747	+0.304	<.001	<.001	3	7
HNSC	NDC1 →	+0.677	+0.136	<.001	<.001	3	7
GBM	VRK1 →	+0.809	+0.319	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,512 associations by consensus.

Exploration

SF3A3 survival (RNA) · tumor vs normal (RNA) · all SF3A3 data types