SF1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,878 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SF1-associated proteins across cancer lineages are ADNP, SF3B3, and NELFCD. Each is linked with SF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SF1-to-partner and partner-to-SF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SF1 versus ADNP in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SF1→partner) and Y-score (partner→SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMADNP →+0.324+0.325<.001.00136
LSCCSF3B3 →+0.232+0.459.001<.00136
HNSCNELFCD →+0.355+0.585<.001.00135
LSCCNXF1 →+0.273+0.576<.001<.00135
LSCCBUB3 →+0.301+0.508<.001<.00135
GBMCPSF7 →+0.381+0.417<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,878 associations by consensus.

SF1 vs ADNP — GBM

Per-sample scatter of SF1 vs ADNP in GBM (Pearson r = 0.43).

Explore this scatter interactively →

Exploration