SF1

Across TCGA cell cohorts, SF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,937 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SF1-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Epigenetic regulation of gene expression, and Negative regulation of gene expression, epigenetic. Each is linked with SF1 in more than 18 cancer types. Because this analysis shows association rather than direction, both SF1-to-partner and partner-to-SF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by SF1-low versus SF1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SF1→partner) and Y-score (partner→SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	mRNA alternative polyadenylation →	+0.118	+0.702	<.001	.001	3	19
STOMACH	Epigenetic regulation of gene expression →	+0.090	+0.759	<.001	.001	3	19
LARGE_INTESTINE	Negative regulation of gene expression, epigenetic →	+0.073	+1.032	<.001	<.001	3	19
URINARY_TRACT	Establishment of RNA localization →	+0.102	+1.303	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA repair →	+0.075	+1.086	<.001	<.001	3	18
BONE	Heterochromatin organization →	+0.078	+1.202	.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,937 associations by consensus.

mRNA alternative polyadenylation by SF1 expression — STOMACH

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