SEZ6L

Across TCGA patient cohorts, SEZ6L protein abundance is significantly associated with the RNA expression of many other genes, with 12,933 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEZ6L-associated genes across cancer lineages are FKBP3, R3HCC1, and FAM83E. Each is linked with SEZ6L in more than 2 cancer types. Because this analysis shows association rather than direction, both SEZ6L-to-partner and partner-to-SEZ6L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEZ6L versus FKBP3 in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEZ6L→partner) and Y-score (partner→SEZ6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FKBP3 →	+0.696	+1.219	.006	.008	3	2
BRCA	R3HCC1 →	+0.676	+1.283	.006	.007	3	2
BRCA	FAM83E →	+2.758	+1.218	.001	.005	3	2
BRCA	RIC8B →	+0.739	+1.900	.001	.002	3	2
BRCA	TRAPPC13 →	+0.607	+1.557	.007	.003	3	2
GBM	TRMT5 →	+0.482	+0.663	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,933 associations by consensus.

SEZ6L vs FKBP3 — BRCA

Explore this scatter interactively →