SETSIP

Across TCGA patient cohorts, SETSIP RNA expression is significantly associated with the protein abundance of many other proteins, with 8,149 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SETSIP-associated proteins across cancer lineages are RPL12_S38, DNAJA1, and DNMT1_S714. Each is linked with SETSIP in more than 3 cancer types. Because this analysis shows association rather than direction, both SETSIP-to-partner and partner-to-SETSIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETSIP versus RPL12_S38 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETSIP→partner) and Y-score (partner→SETSIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL12_S38 →	+0.897	+0.979	<.001	.001	3	4
OV	DNAJA1 →	+0.319	+2.088	<.001	<.001	3	3
LSCC	DNMT1_S714 →	+0.526	+0.269	<.001	<.001	3	3
UCEC	EMC1 →	+0.315	+1.545	<.001	<.001	3	3
LSCC	EZH2_T487 →	+0.650	+0.247	<.001	.001	3	3
LSCC	FCSK →	-0.267	-0.250	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,149 associations by consensus.

SETSIP vs RPL12_S38 — BRCA

Explore this scatter interactively →