SETSIP

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SETSIP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,307 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SETSIP-associated GO terms across cancer lineages are Metaphase/anaphase transition of cell cycle, Nucleic acid transport, and RNA transport. Each is linked with SETSIP in more than 11 cancer types. Because this analysis shows association rather than direction, both SETSIP-to-partner and partner-to-SETSIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase/anaphase transition of cell cycle grouped by SETSIP-low versus SETSIP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SETSIP→partner) and Y-score (partner→SETSIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEMetaphase/anaphase transition of cell cycle →+0.201+0.541<.001<.001312
SOFT_TISSUENucleic acid transport →+0.097+0.380<.001<.001312
SOFT_TISSUERNA transport →+0.097+0.380<.001<.001312
BONEmRNA transport →+0.091+0.350<.001.002312
SOFT_TISSUERNA export from nucleus →+0.114+0.386<.001<.001312
BONEmRNA export from nucleus →+0.103+0.350<.001.002312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,307 associations by consensus.

Metaphase/anaphase transition of cell cycle by SETSIP expression — BONE

Box plot of Metaphase/anaphase transition of cell cycle in SETSIP-low vs SETSIP-high samples in BONE.

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Exploration