SETP6

Across TCGA patient cohorts, SETP6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,076 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SETP6-associated proteins across cancer lineages are GBE1, PLOD1, and SERPINE1. Each is linked with SETP6 in more than 5 cancer types. Because this analysis shows association rather than direction, both SETP6-to-partner and partner-to-SETP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETP6 versus GBE1 in CCRCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETP6→partner) and Y-score (partner→SETP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GBE1 →	+0.432	+0.681	<.001	<.001	3	6
GBM	PLOD1 →	+0.566	+0.540	<.001	<.001	3	5
CCRCC	SERPINE1 →	+0.788	+0.426	.005	.007	3	4
GBM	ITGA5 →	+0.401	+0.463	.001	.002	3	4
PDAC	LOXL2 →	+0.797	+0.498	<.001	<.001	3	4
CCRCC	PLOD2 →	+0.882	+0.508	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,076 associations by consensus.

SETP6 vs GBE1 — CCRCC

Explore this scatter interactively →