SETP2

Across TCGA patient cohorts, SETP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,658 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SETP2-associated proteins across cancer lineages are SURF6_S138, CD109, and FRMD6. Each is linked with SETP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SETP2-to-partner and partner-to-SETP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETP2 versus SURF6_S138 in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETP2→partner) and Y-score (partner→SETP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SURF6_S138 →	+0.955	+0.449	<.001	<.001	3	4
LSCC	CD109 →	+0.433	+0.358	.001	<.001	3	3
LSCC	FRMD6 →	+0.507	+0.528	<.001	<.001	3	3
LSCC	JUNB →	+0.408	+0.395	<.001	.006	3	3
LSCC	SOWAHC →	+0.396	+0.450	<.001	.009	3	3
LSCC	ATP6V1E1 →	-0.207	-0.524	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,658 associations by consensus.

SETP2 vs SURF6_S138 — LSCC

Explore this scatter interactively →