SETP14

Across TCGA patient cohorts, SETP14 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,606 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SETP14-associated proteins across cancer lineages are RPL12_S38, TOP2A_S1377, and SMC2. Each is linked with SETP14 in more than 7 cancer types. Because this analysis shows association rather than direction, both SETP14-to-partner and partner-to-SETP14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETP14 versus RPL12_S38 in BRCA, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETP14→partner) and Y-score (partner→SETP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL12_S38 →	+1.081	+0.920	<.001	<.001	3	8
PDAC	TOP2A_S1377 →	+1.006	+0.513	.004	.008	3	7
BRCA	SMC2 →	+0.629	+0.801	<.001	<.001	3	7
LUAD	MCM2 →	+0.594	+0.286	<.001	<.001	3	7
PDAC	MCM3 →	+0.625	+0.556	<.001	<.001	3	7
LUAD	MCM5 →	+0.565	+0.286	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,606 associations by consensus.

SETP14 vs RPL12_S38 — BRCA

Explore this scatter interactively →