SETP10

Across TCGA pan-cancer cohorts, SETP10 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SETP10’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where SETP10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SETP10 is over-expressed in tumor.

BRCA, KIRP, and HNSC are the cancer types where SETP10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SETP10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.149	.049	2	view →
KIRP	Female	II,III,IV	+0.064	.025	2	view →
HNSC	Male	All	+0.030	.017	2	view →
LIHC	All	All	+0.010	.026	2	view →
ESCA	Female	All	+0.163	<.001	1	view →
COAD	All	All	+0.040	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SETP10–BRCA

Open the BRCA breakdown →