SETMAR

Across TCGA patient cohorts, SETMAR protein abundance is significantly associated with the RNA expression of many other genes, with 18,125 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SETMAR-associated genes across cancer lineages are CRBN, GPALPP1, and MAGI1. Each is linked with SETMAR in more than 6 cancer types. Because this analysis shows association rather than direction, both SETMAR-to-partner and partner-to-SETMAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETMAR versus CRBN in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SETMAR→partner) and Y-score (partner→SETMAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CRBN →	+0.616	+0.473	<.001	<.001	3	7
LSCC	GPALPP1 →	+0.420	+0.230	<.001	.008	3	7
BRCA	MAGI1 →	+0.693	+0.259	<.001	<.001	3	7
UCEC	PGM5 →	+1.030	+0.290	<.001	<.001	3	7
HNSC	FGD5-AS1 →	+0.493	+0.483	<.001	<.001	3	7
GBM	FXYD6 →	+1.027	+0.361	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,125 associations by consensus.

SETMAR vs CRBN — OV

Explore this scatter interactively →