SETMAR

Across TCGA patient cohorts, SETMAR mutation is significantly associated with the RNA expression of many other genes, with 1,847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SETMAR-associated genes across cancer lineages are MIR3651, RNVU1-28, and MTND6P33. Each is linked with SETMAR in more than 1 cancer types. Because this analysis shows association rather than direction, both SETMAR-to-partner and partner-to-SETMAR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3651 grouped by SETMAR-low versus SETMAR-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SETMAR→partner) and Y-score (partner→SETMAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR3651 →	+0.575	+3.881	<.001	.004	3	2
UCEC	RNVU1-28 →	+0.479	+1.857	.001	.001	3	2
CESC	MTND6P33 →	+0.125	+5.252	<.001	.002	3	2
LUAD	UBTFL7 →	+0.222	+5.343	<.001	.006	3	2
LUAD	MIR4716 →	+0.526	+5.798	<.001	.003	3	2
UCEC	H3Y1 →	+0.568	+1.530	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,847 associations by consensus.

MIR3651 by SETMAR expression — SKCM

Explore this box plot interactively →