SETD9

Across TCGA patient cohorts, SETD9 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,129 significant associations in total. THYM shows the largest number of these associations.

The most reproducible SETD9-associated GO terms across cancer lineages are Mitochondrial translational elongation, Positive regulation of rRNA processing, and Maturation of SSU-rRNA. Each is linked with SETD9 in more than 25 cancer types. Because this analysis shows association rather than direction, both SETD9-to-partner and partner-to-SETD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translational elongation grouped by SETD9-low versus SETD9-high in ACC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SETD9→partner) and Y-score (partner→SETD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	Mitochondrial translational elongation →	+0.078	+0.806	<.001	<.001	3	26
DLBC	Positive regulation of rRNA processing →	+0.074	+0.932	<.001	<.001	2	26
DLBC	Maturation of SSU-rRNA →	+0.064	+0.946	<.001	<.001	2	26
UVM	Ribosomal small subunit biogenesis →	+0.046	+0.796	<.001	<.001	3	25
DLBC	Small nucleolar ribonucleoprotein complex assembly →	+0.063	+0.902	<.001	<.001	2	25
DLBC	Regulation of rRNA processing →	+0.063	+0.855	<.001	<.001	2	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,129 associations by consensus.

Mitochondrial translational elongation by SETD9 expression — ACC

Explore this box plot interactively →