SETD9

Across TCGA patient cohorts, SETD9 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SETD9-associated genes across cancer lineages are Endothelial cells, lymphatic Endothelial cells, and mv Endothelial cells. Each is linked with SETD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SETD9-to-partner and partner-to-SETD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by SETD9-low versus SETD9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SETD9→partner) and Y-score (partner→SETD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.052	-3.127	.013	.020	1	1
UCEC	lymphatic Endothelial cells →	-0.029	-3.116	.025	.020	1	1
UCEC	mv Endothelial cells →	-0.030	-3.159	.019	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Endothelial cells by SETD9 expression — UCEC

Explore this box plot interactively →