SETD9

Across TCGA cell cohorts, SETD9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,644 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SETD9-associated GO terms across cancer lineages are Establishment or maintenance of epithelial cell apical/basal polarity, Sensory perception of sour taste, and Protein de-ADP-ribosylation. Each is linked with SETD9 in more than 5 cancer types. Because this analysis shows association rather than direction, both SETD9-to-partner and partner-to-SETD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of epithelial cell apical/basal polarity grouped by SETD9-low versus SETD9-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SETD9→partner) and Y-score (partner→SETD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Establishment or maintenance of epithelial cell apical/basal polarity →	-0.137	-1.421	<.001	.001	3	6
BONE	Sensory perception of sour taste →	-1.205	-1.168	<.001	<.001	3	6
BONE	Protein de-ADP-ribosylation →	-0.208	-0.993	<.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of lymphocyte proliferation →	-0.066	-0.895	.008	.007	3	5
OESOPHAGUS	Establishment or maintenance of apical/basal cell polarity →	-0.135	-1.279	<.001	.004	3	5
OESOPHAGUS	Regulation of fat cell differentiation →	-0.070	-1.542	.008	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,644 associations by consensus.

Establishment or maintenance of epithelial cell apical/basal polarity by SETD9 expression — OESOPHAGUS

Explore this box plot interactively →