SETD1B

Across TCGA patient cohorts, SETD1B protein abundance is significantly associated with the protein abundance of many other proteins, with 12,083 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SETD1B-associated proteins across cancer lineages are SETD1B_T381, MEN1, and PBRM1. Each is linked with SETD1B in more than 5 cancer types. Because this analysis shows association rather than direction, both SETD1B-to-partner and partner-to-SETD1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SETD1B versus SETD1B_T381 in GBM, with a Pearson correlation of 0.45.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SETD1B→partner) and Y-score (partner→SETD1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SETD1B_T381 →	+0.542	+0.316	<.001	<.001	3	6
GBM	MEN1 →	+0.313	+0.245	<.001	<.001	3	6
GBM	PBRM1 →	+0.298	+0.211	<.001	<.001	3	5
OV	SART3 →	+0.259	+0.260	<.001	<.001	3	5
GBM	SIN3A →	+0.290	+0.275	<.001	<.001	3	5
LSCC	TRRAP →	+0.197	+0.139	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,083 associations by consensus.

SETD1B vs SETD1B_T381 — GBM

Explore this scatter interactively →