SESN1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SESN1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SESN1-associated genes across cancer lineages are CT45A2. Each is linked with SESN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SESN1-to-partner and partner-to-SESN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CT45A2 grouped by SESN1-low versus SESN1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SESN1→partner) and Y-score (partner→SESN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECT45A2 →+0.025+4.054<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CT45A2 by SESN1 expression — LARGE_INTESTINE

Box plot of CT45A2 in SESN1-low vs SESN1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration