SERTAD4

Across TCGA cell cohorts, SERTAD4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SERTAD4-associated genes across cancer lineages are CD300H, CCDC172, and LCE2A. Each is linked with SERTAD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERTAD4-to-partner and partner-to-SERTAD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by SERTAD4-low versus SERTAD4-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERTAD4→partner) and Y-score (partner→SERTAD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CD300H →	+0.118	+5.169	<.001	<.001	3	1
BLOOD_Leukemia	CCDC172 →	+0.046	+5.201	.005	.006	3	1
BLOOD_Leukemia	LCE2A →	+0.071	+5.969	<.001	.001	3	1
LUNG_SCLC	BTNL3 →	+0.110	+4.025	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD300H by SERTAD4 expression — LUNG_SCLC

Explore this box plot interactively →