SERPING1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SERPING1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,779 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SERPING1-associated genes across cancer lineages are VGLL3, MMP19, and GFPT2. Each is linked with SERPING1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SERPING1-to-partner and partner-to-SERPING1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPING1 versus VGLL3 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPING1→partner) and Y-score (partner→SERPING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVVGLL3 →+1.235+0.647<.001<.001310
OVMMP19 →+1.608+0.719<.001<.00139
OVGFPT2 →+1.519+0.560<.001<.00139
OVAOC3 →+1.977+0.699<.001<.00139
BRCAHSPA12B →+0.999+0.653<.001<.00139
OVDIPK2B →+1.062+0.747<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,779 associations by consensus.

SERPING1 vs VGLL3 — OV

Per-sample scatter of SERPING1 vs VGLL3 in OV (Pearson r = 0.47).

Explore this scatter interactively →

Exploration