SERPING1

Across TCGA cell cohorts, SERPING1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,749 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SERPING1-associated genes across cancer lineages are COMMD6, KAT14, and B3GNT9. Each is linked with SERPING1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SERPING1-to-partner and partner-to-SERPING1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPING1 versus COMMD6 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPING1→partner) and Y-score (partner→SERPING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	COMMD6 →	+0.839	+1.305	<.001	<.001	3	4
BLOOD_Myeloma	KAT14 →	-0.591	-0.744	.009	.004	3	4
SKIN	B3GNT9 →	+1.153	+0.826	.001	<.001	3	4
LUNG_SCLC	PAM →	+1.963	+0.895	.002	.007	3	4
KIDNEY	TNFSF10 →	+3.758	+0.787	<.001	.001	3	3
STOMACH	NIPSNAP3A →	+1.633	+0.808	.003	.009	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,749 associations by consensus.

SERPING1 vs COMMD6 — LUNG_NSCLC_LUSC

Explore this scatter interactively →