SERPINF1

Across TCGA pan-cancer cohorts, SERPINF1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SERPINF1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SERPINF1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SERPINF1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

COAD, LSCC, and UCEC are the cancer types where SERPINF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.882	1.000	.016	36	view →
LSCC	DFS	Median	All	0.591	0.818	.002	22	view →
UCEC	DFS	Tertile	III,IV	0.366	1.000	.020	20	view →
LUAD	OS	Quartile	III,IV	0.374	0.867	.008	5	view →
GBM	OS	Quartile	All	0.242	0.571	.026	5	view →
CCRCC	DFS	Median	All	0.838	0.654	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SERPINF1–COAD (DFS)

Open the COAD breakdown →