SERPINE3

Across TCGA patient cohorts, SERPINE3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,430 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SERPINE3-associated proteins across cancer lineages are RBM26, PLEC_S1888, and PLEC_S2039. Each is linked with SERPINE3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SERPINE3-to-partner and partner-to-SERPINE3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINE3 versus RBM26 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINE3→partner) and Y-score (partner→SERPINE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBM26 →	+0.237	+0.573	<.001	.001	3	4
GBM	PLEC_S1888 →	-0.554	-0.500	.002	.005	3	3
GBM	PLEC_S2039 →	-0.554	-0.500	.002	.005	3	3
OV	ATXN2L_S168 →	-1.002	-0.416	.002	.002	3	3
GBM	SND1_S645 →	-0.690	-0.543	.004	.002	3	3
GBM	ITPR3 →	-0.599	-0.463	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,430 associations by consensus.

SERPINE3 vs RBM26 — GBM

Explore this scatter interactively →