SERPINE2

Across TCGA patient cohorts, SERPINE2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,590 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SERPINE2-associated proteins across cancer lineages are MMP2, COL16A1, and FBLN2. Each is linked with SERPINE2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SERPINE2-to-partner and partner-to-SERPINE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINE2 versus MMP2 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINE2→partner) and Y-score (partner→SERPINE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MMP2 →	+0.645	+0.746	<.001	<.001	3	6
COAD	COL16A1 →	+0.923	+1.210	<.001	<.001	3	6
BRCA	FBLN2 →	+0.826	+1.133	<.001	<.001	3	6
BRCA	SERPINF1 →	+0.717	+0.998	<.001	<.001	3	5
COAD	SFRP2 →	+1.300	+1.079	<.001	.001	3	5
COAD	SRPX2 →	+0.826	+1.166	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,590 associations by consensus.

SERPINE2 vs MMP2 — BRCA

Explore this scatter interactively →