SERPINE2

Across TCGA patient cohorts, SERPINE2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,881 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SERPINE2-associated genes across cancer lineages are COMP, SFRP4, and SFRP2. Each is linked with SERPINE2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SERPINE2-to-partner and partner-to-SERPINE2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINE2 versus COMP in COAD, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINE2→partner) and Y-score (partner→SERPINE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	COMP →	+1.861	+0.958	<.001	<.001	3	7
COAD	SFRP4 →	+1.986	+0.758	<.001	<.001	3	7
COAD	SFRP2 →	+2.426	+0.809	<.001	<.001	3	7
CCRCC	PRELP →	+1.362	+0.674	<.001	<.001	3	7
CCRCC	CCDC80 →	+1.362	+0.735	<.001	<.001	3	7
UCEC	CPED1 →	+1.199	+0.948	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,881 associations by consensus.

SERPINE2 vs COMP — COAD

Explore this scatter interactively →