SERPINC1

Across TCGA patient cohorts, SERPINC1 RNA expression is significantly associated with the RNA expression of many other genes, with 11,563 significant associations in total. UVM shows the largest number of these associations.

The most reproducible SERPINC1-associated genes across cancer lineages are LEAP2, ALB, and APOC3. Each is linked with SERPINC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SERPINC1-to-partner and partner-to-SERPINC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINC1 versus LEAP2 in CHOL, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINC1→partner) and Y-score (partner→SERPINC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	LEAP2 →	+1.538	+3.960	<.001	<.001	3	20
CHOL	ALB →	+7.202	+6.574	<.001	<.001	2	20
CHOL	APOC3 →	+6.433	+4.916	<.001	<.001	3	19
CHOL	APOA2 →	+4.908	+3.972	<.001	<.001	3	18
LIHC	ALDH8A1 →	+0.999	+1.381	<.001	<.001	3	18
CHOL	HPX →	+4.126	+4.520	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,563 associations by consensus.

SERPINC1 vs LEAP2 — CHOL

Explore this scatter interactively →