SERPINC1

Across TCGA patient cohorts, SERPINC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,811 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SERPINC1-associated GO terms across cancer lineages are Macromolecule deacylation, Lipoprotein biosynthetic process, and Mitochondrial cytochrome c oxidase assembly. Each is linked with SERPINC1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SERPINC1-to-partner and partner-to-SERPINC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule deacylation grouped by SERPINC1-low versus SERPINC1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINC1→partner) and Y-score (partner→SERPINC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Macromolecule deacylation →	+0.064	+0.276	.003	<.001	2	13
STAD	Lipoprotein biosynthetic process →	+0.052	+0.197	<.001	<.001	3	11
STAD	Mitochondrial cytochrome c oxidase assembly →	+0.055	+0.253	<.001	<.001	3	11
STAD	Protein deacetylation →	+0.087	+0.304	<.001	<.001	2	12
STAD	Nucleoside triphosphate biosynthetic process →	+0.066	+0.205	<.001	<.001	3	10
STAD	Phospholipid biosynthetic process →	+0.052	+0.154	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,811 associations by consensus.

Macromolecule deacylation by SERPINC1 expression — SCLC

Explore this box plot interactively →