SERPINC1

Across TCGA patient cohorts, SERPINC1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,655 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINC1-associated genes across cancer lineages are STK33, MDH1B, and ZNF675. Each is linked with SERPINC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINC1-to-partner and partner-to-SERPINC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINC1 versus STK33 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINC1→partner) and Y-score (partner→SERPINC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STK33 →	+0.927	+0.897	<.001	<.001	3	3
UCEC	MDH1B →	+1.609	+1.280	<.001	<.001	3	3
UCEC	ZNF675 →	-0.533	-0.706	.003	.008	3	2
UCEC	C2orf73 →	+0.896	+1.051	<.001	<.001	3	2
UCEC	CYCSP25 →	+0.808	+0.786	.003	.004	3	2
LSCC	UFD1 →	-1.003	-1.490	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,655 associations by consensus.

SERPINC1 vs STK33 — UCEC

Explore this scatter interactively →