SERPINC1

Across TCGA cell cohorts, SERPINC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,506 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SERPINC1-associated GO terms across cancer lineages are Golgi vesicle transport, Regulation of RNA splicing, and Autophagosome organization. Each is linked with SERPINC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SERPINC1-to-partner and partner-to-SERPINC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by SERPINC1-low versus SERPINC1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINC1→partner) and Y-score (partner→SERPINC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Golgi vesicle transport →	+0.047	+0.161	.005	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.067	+0.103	<.001	<.001	3	7
PANCREAS	Autophagosome organization →	+0.067	+0.213	<.001	.006	3	7
BLOOD_Lymphoma	Regulation of response to endoplasmic reticulum stress →	+0.044	+0.064	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of transcription elongation by RNA polymerase II →	+0.044	+0.075	.009	.008	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.082	+0.095	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,506 associations by consensus.

Golgi vesicle transport by SERPINC1 expression — PANCREAS

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