SERPINB9

Across TCGA patient cohorts, SERPINB9 protein abundance is significantly associated with the RNA expression of many other genes, with 16,380 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERPINB9-associated genes across cancer lineages are IL21R, CD37, and LILRB1. Each is linked with SERPINB9 in more than 9 cancer types. Because this analysis shows association rather than direction, both SERPINB9-to-partner and partner-to-SERPINB9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINB9 versus IL21R in GBM, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB9→partner) and Y-score (partner→SERPINB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IL21R →	+1.094	+0.433	<.001	<.001	3	10
BRCA	CD37 →	+0.847	+0.498	<.001	<.001	3	10
UCEC	LILRB1 →	+1.217	+0.620	<.001	<.001	3	10
GBM	JAK3 →	+1.162	+0.454	<.001	<.001	3	10
HNSC	SELPLG →	+1.104	+0.454	<.001	<.001	3	10
GBM	CD86 →	+1.090	+0.420	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,380 associations by consensus.

SERPINB9 vs IL21R — GBM

Explore this scatter interactively →