SERPINB9

Across TCGA cell cohorts, SERPINB9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,603 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SERPINB9-associated GO terms across cancer lineages are Protection from natural killer cell mediated cytotoxicity, Negative regulation of protein modification process, and Alpha-beta T cell activation involved in immune response. Each is linked with SERPINB9 in more than 10 cancer types. Because this analysis shows association rather than direction, both SERPINB9-to-partner and partner-to-SERPINB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protection from natural killer cell mediated cytotoxicity grouped by SERPINB9-low versus SERPINB9-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB9→partner) and Y-score (partner→SERPINB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protection from natural killer cell mediated cytotoxicity →	-0.204	-2.155	.001	<.001	3	11
BREAST	Negative regulation of protein modification process →	+0.074	+1.075	<.001	.002	3	7
STOMACH	Alpha-beta T cell activation involved in immune response →	+0.092	+1.850	.002	.001	3	6
STOMACH	T cell differentiation involved in immune response →	+0.092	+1.850	.002	.001	3	6
STOMACH	CD4-positive, alpha-beta T cell differentiation →	+0.099	+2.511	<.001	<.001	3	6
KIDNEY	Regulation of ATP biosynthetic process →	+0.090	+1.781	.003	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,603 associations by consensus.

Protection from natural killer cell mediated cytotoxicity by SERPINB9 expression — STOMACH

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